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General physicians (GPs) are not currently authorised to prescribe semaglutide, though this may change as the market evolves
Additionally, some novel GLP-1s hold promise for improved tolerability, as evidenced by Structure Therapeutics phase 2 data for GSBR-1290, which demonstrated encouraging results in terms of AEs and discontinuation rates
Ozempic, a once-weekly injection used for the treatment of type 2 diabetes, has skyrocketed in use after people were reportedly prescribed the FDA-approved diabetes medication as an off-label weight loss drug
Blood 106:213a, 2005
The 2024 multi-society guidance The 2024 multi-society guidance substantially changed the clinical approach
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